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Author: Dr. Ritu Agarwal

  • Laser Assisted Hatching (LAH) in IVF

    Laser Assisted Hatching (LAH) in IVF

    In the field of assisted reproductive technology, a method known as laser-assisted hatching, which is often commonly referred to as “laser hatching,” has recently emerged as a ground-breaking approach to improve the success rates of in vitro fertilization (IVF) cycles. This cutting-edge treatment has provided infertile couples with access to previously unavailable options and opportunities. Ritu IVF Centre is at the forefront of implanting this innovative therapy to its patients, giving those who are hoping to grow their families a glimmer of hope in the process.

    What Exactly does “Laser Assisted Hatching” refer to?

    During the in-vitro fertilization (IVF) procedure, a specialized method known as laser-assisted hatching is used to aid in the implantation of the embryo into the uterine lining. The zona pellucida is the protective outer layer that surrounds the embryo. The method includes the precise use of a laser to generate a tiny hole or thinning in the zona pellucida. This delicate process done by embryologists makes it possible for the embryo to more readily break free from its protective shell, which in turn promotes its attachment to the woman’s uterus (uterine wall )and increases the chances of a healthy pregnancy.

    The Science Behind Laser-Assisted Hatching in IVF

    Medical experts perform laser hatching at a critical stage in the in vitro fertilization process. Following fertilization, the embryo immediately enters the zona pellucida, where it will continue to grow. The (blastocyst) embryo has to be able to escape from this protective layer for the implantation process to be effective. On the other hand, the pellucida may be abnormally thick or rigid in some instances, making it impossible for the embryo to emerge normally. At this stage, it is possible to use lasers to assist with hatching.

    In laser hatching, a focused laser beam creates a precise opening in the pellucida, allowing the embryo to emerge from its shell. This controlled, non-invasive method increases the chances of a healthy pregnancy and successful implantation.

    The Probability of Successful Laser-Assisted Hatching(LAH)

    The use of lasers to help in embryo hatching has shown some encouraging outcomes in terms of increasing the success rates of in vitro fertilization procedures. According to the findings of several studies, this procedure may be of particular benefit to specific categories of patients, including older women and those who have had prior attempts at IVF failure. However, it is essential to keep in mind that the effectiveness of laser hatching might differ from case to case depending on the specifics of the situation.

    FAQs Regarding Laser-Assisted Hatching Technique

    How much does it cost to hatch eggs with the help of an IVF laser-assisted hatching?

    The cost of laser-assisted hatching may vary depending on the IVF center, its location, and the patient’s specific needs. In most cases, there is an added cost associated with it on top of the cost of the conventional IVF operation.

    When is the use of laser-assisted hatching advised?

    Here are some situations in which medical professionals often recommend laser-assisted hatching:

    • Previous IVF rounds that were unsuccessful
    • Advanced years of age for the mother
    • Unusual appearance of the zona pellucida
    • High amounts of the hormone FSH
    • Zone pellucid that has become more dense

    Is the embryo in any danger during the laser-assisted hatching process?

    When knowledgeable medical experts perform assisted hatching, they consider it a safe procedure that causes only minimal discomfort for the patient.

     When using frozen embryos, is it possible to hatch them with laser assistance?

    The answer to your question is that it is possible to conduct laser-assisted hatching on frozen embryos before transferring them during a frozen embryo transfer (FET) cycle.

    Ritu IVF Center: Setting the Standard for Excellence

    The Ritu IVF Fertility Center is committed to offering cutting-edge reproductive treatments, such as assisted hatching, to its patients. Ritu IVF Center is dedicated to assisting individuals and couples in realizing their goals of becoming parents by providing them with access to an experienced staff of fertility doctors as well as technologically advanced equipment.

    Conclusion

    IVF has made incredible strides forward in recent years, and one of those steps has been the development of laser-assisted hatching, which gives those struggling with infertility a new source of hope. This method has become standard practice in almost all aspects of the in vitro fertilization process due to its high rate of success and little potential for adverse effects. Ritu IVF Center in Jaipur is a reliable partner for those who are just starting on their path to becoming parents because of the center’s dedication to providing exceptional care. The use of lasers to help eggs hatch is an exciting new advancement that will undoubtedly have a significant impact on the field of assisted reproduction in the future.

  • Egg Freezing Process: Preserving Fertility for the Future

    Egg Freezing Process: Preserving Fertility for the Future

    It’s more normal than it used to freeze your eggs to put off getting pregnant. If you choose to freeze your eggs, you can take care of other things in your life until you’re ready to get pregnant. This is helpful if you want to start a job, find a partner, or deal with health issues.

    People don’t think twice about freezing eggs anymore, but not everyone knows the whole process. To make an informed choice, you need to know what to expect, how much it will cost, and how egg saving can help you stay fertile.

    How do you Freeze Eggs?

    When eggs are frozen, they can be used in assisted reproductive technology (ART). This is also known as embryo cryopreservation.

    Medications are used to help the eggs grow during the process. The eggs are then taken out of the ovaries and frozen to keep them safe. The eggs can be warmed and mixed with sperm at a later time to make a baby. During the embryo transfer stage, the egg can then be put into the uterus.

    Some people choose to freeze their eggs so that they can be used later. Freezing eggs is also done by people who donate them so that someone else can use them during fertility treatments.

    No matter because you want to freeze eggs, the end goal is the same: keeping eggs lets you keep your fertility by collecting eggs at a younger age that can be used later. This won’t guarantee a pregnancy, but it can make it more likely that you’ll be able to get pregnant later in life.

    How To Egg Freezing and When to Do It

    You can expect the whole process of freezing eggs to take between 2 and 3 weeks, though exact times may change. It’s possible to finish most rounds in less than two weeks.

    To get the best results, stimulating the ovaries to make eggs at the right time for you is timed with your period. Ultrasounds and blood tests to check hormone levels are used to carefully watch the ovaries during this process.

    Medical Check-up

    You will first need to talk to a fertility doctor about your plan to freeze your eggs. Your doctor will set up an appointment for an exam, during which they will look at your medical history, do blood work, and test your hormones.

    A transvaginal ultrasound will also be used to do an antral follicle count (AFC). This is a way to measure your ovarian reserve or the number of eggs that are still in your ovaries.

    During this time, your fertility doctor will talk to you about the best way to stimulate your ovaries so that you can safely get the most eggs without getting ovarian hyperstimulation syndrome (OHSS).

    This is a reaction that can happen after a woman gets hormone shots during ovary stimulation.

    Your doctor will also give you an idea of how many eggs they think they will be able to retrieve and tell you how to take the medicines that will trigger your ovaries and get them ready for retrieval.

    Monitoring and Stimulating the Ovaries

    Starting this process might involve taking birth control pills or other drugs like estrogen, lupron, or Aygestin, depending on what your doctor says and where you are in your menstrual cycle. These drugs will help your follicles get ready for the stimulation drugs you’ll be taking later.

    If you receive instructions to take birth control or other medications that regulate your periods. You will usually start doing so during your period or right after you ovulate.

    To make sure you start stimulation shots at the right time, you will still be checked on with either blood tests or ultrasounds. Once you’re given the all-clear to start shots, your doctor or treatment planner will give you clear advice on how to give yourself the injections.

    Most people will take gonadotropins, which are hormones like follicle-stimulation hormone (FSH) and luteinizing hormone (LH). These hormones tell the ovaries to make more than one egg during a cycle.

    It will take about 10 to 12 days of straight shots of these medicines under the skin in the belly. We closely monitor you during those days, and based on how your body responds to the injections, your doctor may adjust the dosage and combination of your medications.

    From day 5 to day 7, your eggs may start to get bigger, so don’t be surprised if your doctor tells you not to do hard activities like running or high-impact workouts during this time.

    Most of the time, you will have three to five tracking visits during the stimulation process to see how your follicles are doing. A trigger shot, which is an injection of medicine, is given once the follicles are big enough. The medicine is usually human chorionic gonadotropin (hCG), lupron, or a mix of the two.

    Getting Egg Retrieval

    Egg removal, which is also called egg picking, is the process of getting eggs out of your ovaries. As part of this process, you will go to your doctor’s office or clinic and be given an IV. This will let them give you general anesthesia for the surgery since you’ll be asleep during it.

    Your doctor will use a transvaginal ultrasound tool with a needle to get the eggs. The needle will be put into your follicles with the help of the ultrasound. The fluid that holds the eggs inside the follicles is sucked out and put into tubes, which are then given to an embryologist.

    The embryologist will look at the follicle fluid to find the eggs. It takes about 10 to 20 minutes to finish the whole process. Your doctor will tell you how many eggs were taken out when you wake up.

    A lot of things affect how many eggs are removed, but age and ovarian reserve are the two most important ones. People aged 40 and up tend to have fewer eggs taken than people younger than 35.

    Getting Better Egg Freezing Process

    In the 24 hours after egg removal, it’s normal to have cramps, bloating, constipation, and spotting in the pelvic area. Over-the-counter painkillers or warm pads can help most people feel better.

    Call your doctor right away if you have more intense stomach pain, feel dizzy or faint, or have heavy vaginal blood.

    Once we safely collect the developed eggs, we quickly freeze them using a process called vitrification. By rapidly freezing the eggs with liquid nitrogen, we reduce the chance of ice crystals forming and increase the number of eggs that survive.

    Who Might Thinking About Egg Freezing Procedure

    Egg freezing can serve many purposes, but the most common are delaying pregnancy, preserving fertility, or donating eggs.

    Many people, especially those in their 20s or early 30s, choose to put off having children to advance their careers or for other reasons. Putting eggs in the freezer when you’re younger will help you get more babies if you ever need or want to use them.

    On the other hand, people with serious health problems that could affect their ability to have children, like cancer, polycystic ovarian syndrome (PCOS), or endometriosis, may be told to freeze their eggs before starting treatment to keep their fertility.

    Also, people who were born with ovaries and want to change their gender and may start treatment like hormone therapy or surgery may freeze their eggs to keep their fertility for the future.

    Risk And Side-Effects Of Egg-Freezing Process

    The process involves some risks. Most people will only feel pain during the injections and right after the egg extraction. Ovarian hyperstimulation syndrome, or OHSS, can happen very rarely to a patient.

    OHSS can happen when the medicines used to make the ovaries make more eggs also raise hormone levels very high. This can make the ovaries get bigger, fluid leaks into the belly, and chemical problems happen.

    Researchers have found that this side effect is more likely to happen to people younger than 35. In the same way, people who already have diseases like PCOS or a low body mass index (BMI) may be more likely to get OHSS.

    Also, keep in mind that changes in your hormones during a normal monthly cycle can affect your mood, and so can stimulant drugs. Freezing eggs can cause stress, which can get worse when you take hormone medicines.

    Injections of hormones and stimulation of the ovaries can also cause skin soreness at the injection sites and ovarian torsion, a rare disease in which the ovary turns on itself and cuts off its blood supply. It can be really painful.

    How Much Cost Consider Egg Freezing

    Egg freezing costs a lot of different amounts, based on where you live and which center you go to. Know this: Most insurance plans won’t pay for this process unless your pregnancy is in danger because of a health problem like cancer.

    We price egg freezing by cycles, which usually include the process of stimulating the eggs (we give them medicine and monitor their growth) until we remove and freeze them.

    It can cost anywhere from $5,000 to $10,000 per cycle to freeze eggs. The total cost of the cycle may go up when you add in the cost of the medicines, which can be anywhere from $2,000 to $7,000 based on the amount and mix of medicines that are given.

    You should also think about how much it will cost to store your eggs. The center determines the exact amount that this will cost each year, which may be $500 to $1,000.

    If you want to freeze your eggs, look for centers that let you pay over time. You could also move to an insurance company that covers freezing eggs.

    There are funding programs for fertility, like the Hope for Fertility Foundation, the Baby Quest Foundation, and the Cade Foundation.

    People who want to freeze their eggs as a way to avoid having a health problem that could make them unable to have children should look into grant programs that are specifically for this purpose. Livestrong Fertility, the Heart Beat Programme, and Fertility Within Reach are all great choices.

    What should you do to get ready to freeze eggs?

    You might want to bring a partner, a trusted friend, or a family member with you on the day of your egg harvesting process. Wear clothes that are easy to move around in, and plan to relax right away after the process. It’s normal to need a few days to get over the pain of extraction.

    Also, it helps to know what to expect. Prepare yourself for a small change in your life, at least while we freeze your eggs.

    Watch what you eat and drink as little coffee and alcohol as possible. In the meantime, do what your doctor tells you to do, especially if they tell you to stay away from more intense things like sex or high-impact exercise.

    You might feel a little more worried or have mood swings because of the drugs you’re taking. Take it easy and be kind to yourself.

    Conclusion

    Studies show that egg freezing helps people who want to maintain fertility, whether they worry about their health, want to delay having children or plan to change their gender. It might not be possible for everyone to afford it, but some programs can help lower the cost.

    It takes a couple of weeks of treatment. The chance to keep your fertility can have many perks that make it worth it.

    FAQs regarding the process of egg freezing 

    Is it painful to freeze an egg?

    Do remember that you will be asleep during the process. However, it’s normal to feel some cramps, soreness, or aches right after the operation.

    How old should you be to freeze your eggs?

    Most women are most fertile when they are 30 years old (Source). Many factors determine what happens next, like the receiver’s age and the number and type of eggs they use.

    Is there anything that could go wrong with a fetus that comes from a frozen egg?

    There are no known risks for fetuses that grow from frozen eggs, as long as there are no underlying illnesses. But once you’ve put eggs and sperm together to make a baby, you can choose to do preimplantation genetic testing, or PGT, on it to check for chromosomal problems.

    What are the chances of getting pregnant with frozen eggs?

    Many factors determine what happens next, like the receiver’s age and the number and type of eggs they use.

    If you are under 35 years old and freeze 20 eggs, one study found that you will have at least one live birth. People who freeze only 5 eggs are 5.9% less likely to have a live birth.

  • Gestational diabetes: Symptoms, Cause, Diagnosis, Treatment

    A positive indicator of diabetes mellitus is high blood sugar levels. One of the forms of diabetes that may develop during pregnancy is called gestational diabetes. This kind of diabetes is caused by shifts in hormone levels.

    Diabetes was not present in the bodies of women who developed gestational diabetes before they became pregnant.

    Symptoms Of Gestational Diabetes

    The following are some of the signs and symptoms that are related with gestational diabetes:

    • Urination that is both more frequent and intense
    • Dry mouth Exhaustion Increased thirst
    • Sickness and throwing up
    • Loss of weight while having an increased hunger
    • A vision that is hazy
    • Infections caused by yeast

    Despite this, many pregnant women with gestational diabetes do not experience any of the classic signs and symptoms of the condition. Because of this, it is advised that screening tests for the disorder be administered to all pregnant women.

    What Causes Gestational Diabetes and Its Risk Factors

    Like developing type 2 diabetes, maternal diabetes happens when the body can’t act properly to insulin. This is known as insulin resistance.

    When cells in the body don’t receive glucose properly, the simple sugar builds up in the bloodstream. This makes blood tests show that blood glucose levels are too high.

    Changes in hormones are the main cause of insulin resistance in pregnant women.

    Some chemicals in the placenta are to blame for gestational diabetes. “In people who are vulnerable, these can make insulin resistance worse.” No one knows for sure why some women can’t handle these hormones well and end up getting gestational diabetes.

    Among these chemicals are:

    • Hormones for growth
    • Cortisol is a stress chemical.
    • Having estrogen and progesterone
    • A hormone called human placental lactogen is made in the placenta and helps break down fat from the mother so that the baby can get energy.
    • Placental insulin is another hormone that stops insulin from working and comes from the placenta.

    During pregnancy, you may also have more diet, exercise less, and have bigger fat deposits, all of which can make insulin resistance worse.

    These changes make it possible for the growing baby to get more nutrients. In response, the woman’s body makes more insulin, but this extra insulin isn’t always enough to keep glucose levels normal, which can lead to type of diabetes.

    There are many things that can make a pregnant woman more likely to get gestational diabetes, such as

    Blood sugar that is high but not high enough to be called diabetes is called prediabetes.

    • A high blood pressure
    • Having a history of gestational diabetes yourself or in your family
    • A history of type 2 diabetes in the family
    • Having problems with your hormones, like polycystic ovarian syndrome (PCOS),
    • Having too much weight or being overweight during pregnancy being more than 25
    • Being from a Pacific Islander, American Indian, Asian, Hispanic, or African background
    • Giving birth to a baby that weighed at least 9 pounds or had a birth problem before
    • Having had a mysterious loss or miscarriage in the past

    Still, some women who don’t have any of these risk factors may still get gestational diabetes because they can’t handle the hormones that come from the placenta.

    Signs of Gestational Diabetes

    Between 24 and 28 weeks of pregnancy, if you’re not at a high risk for gestational diabetes, your doctor will check you for it. Women who are more likely to get gestational diabetes may be checked for it earlier, usually at their first pregnancy visit.

    Some tests that can find gestational diabetes are:

    Challenge Test for Glucose For this test, you will drink a glucose syrup solution and then check your blood sugar level an hour later. A blood sugar reading below 140 mg/dL, or 7.8 mmol/L, is usually thought to be normal. If your blood sugar level is 190 mg/dL or 10.6 mmol/L, you may have gestational diabetes.

    Tests to Check Glucose Again If the first glucose challenge test showed that your blood sugar level was higher than usual, you will need to do another one to find out if you have diabetes. The glucose solution in this test will be sweeter than the first one, and your blood will be checked every hour for three hours. These blood tests will tell you if you have gestational diabetes if two of them come back high.

    Gestational Diabetes: What to Expect

    Most of the time, gestational diabetes is short-term. For more than three-quarters of women who get it, their blood sugar levels return to normal after the pregnancy is over.

    However, women who have had diabetes are more likely to get it again during future pregnancies. They are also more likely to get type 2 diabetes later in life. Because of this, women who have had diabetes should keep getting their blood sugar levels checked, even after they are no longer pregnant.

    Duration Of Gestational Diabetes

    When diabetes shows up during pregnancy, it usually goes away right after giving birth, but this doesn’t always happen.

    If it is true gestational diabetes, it should go away right away after birth,  This is because the metabolic and hormonal changes during pregnancy cause insulin resistance. However, when telling a woman she has gestational diabetes while she is pregnant, it’s sometimes because she already had it before she got pregnant.”

    Pre- gestational diabetes is a type of diabetes that starts before pregnancy. It includes type 1 diabetes and type 2 diabetes, as well as some less common types, like diabetes caused by medicine or diabetes caused by cystic fibrosis. Diabetes during pregnancy will not go away after giving birth.

    To find out if the woman had prenatal diabetes or pregestational diabetes,  a glucose test must be done at the postpartum visit. This lets your doctor check for insulin resistance and diabetes that starts before you get pregnant.

    Your doctor may talk to you about a treatment plan if you were diagnosed with pregestational diabetes while you were pregnant. This could mean making changes to your food and way of life, as well as called insulin or oral medicines.

    Medicines and Treatment For Gestational Diabetes

    People who have gestational diabetes can control it by closely watching their blood sugar, making changes to their lifestyle, and sometimes by taking medicine.

    Keep an eye on your low blood sugar. There may be times during the day when your doctor will tell you to check your blood sugar if you have gestational diabetes.

    The American Diabetes Association (ADA) tells pregnant women who test their blood sugar to aim for the following levels:

    • Less than 95 mg/dL before a meal
    • Less than 140 mg/dL an hour after a meal
    • 120 mg/dL or less two hours after a meal

    Eat well and stay healthy. It’s too bad that the risk of developing gestational diabetes won’t go away while the woman is still pregnant. All those metabolic changes that cause insulin resistance are still happening. However, diet alone can sometimes control it.

    Women should eat 30 to 40 percent carbohydrates and you should choose carbs that are digested more slowly and don’t cause blood sugar to rise too quickly. Most of these foods have a lot of fiber. You could eat whole wheat bread instead of white bread or whole fruit instead of fruit juice. You can find a qualified diabetes care and education specialist and a registered dietitian nutritionist through the Association of Diabetes Care and Education Specialists. These professionals can help you make a diet that is good for a healthy pregnancy.

    Do some movement. Talk to your doctor about how much and what kind of exercise is best for you while you’re pregnant. Fay usually tells all of her patients to work out for 30 minutes at least five days a week. She also says that going for a walk after meals can help lower blood sugar.

    Take your medicine. Changing the way you live might not always be enough to control if diagnosed with gestational diabetes. If blood sugar levels remain high even after changing the diet, doctors use insulin to treat gestational diabetes. “This is safe for pregnant women and reduces your risk.

    You will learn how to give yourself insulin shots with a small needle from your doctor. Some doctors might give you a different pill to swallow.

    How to Avoid Risk For Gestational Diabetes

    While there is no surefire way to avoid getting gestational diabetes, there are things you can do to make it less likely.

    Eating right and staying at a healthy weight before and during pregnancy, as well as getting more exercise, are the best ways to lower your risk of getting gestational diabetes

    If you want to have a better baby, you might want to lose this extra weight before you get pregnant.

    Fruits, veggies, and whole grains are all healthy foods that are low in fat and high in fiber. Every day, try to do some kind of mild exercise for at least 30 minutes. You can make changes to these healthy habits that will last and help you through your pregnancy.

    Although, women who are a healthy weight, work out, and eat well may still get diabetes sometimes. In these situations, it’s likely to happen because of how maternal chemicals work. Gestational diabetes is more likely to happen in women who have a first-degree cousin (like a mother or father) with diabetes. This suggests that genetics may also play a role.

    Complications Of Gestational Diabetes

    There are many problems that can happen for both the mother and the baby when a woman has diabetes. Some risks of gestational diabetes are:

    If you do not take good care of your Extra-Large Baby’s Diabetes, the baby’s blood sugar can rise, which can cause them to be “overfed” and grow extra-large. Fay says, “This can raise the risk of needing a cesarean delivery or shoulder dystocia during vaginal delivery. Shoulder dystocia occurs when the baby’s head delivers, but the shoulders become lodged behind the pubic bone. This can raise the risk of birth trauma.”

    Preeclampsia or high blood pressure: Gestational diabetes can make a woman more likely to get preeclampsia, a dangerous form of high blood pressure that can cause early delivery. It can also make the woman more likely to have seizures or a stroke during labor and delivery.

    Hypoglycemia means low blood sugar: People who have diabetes and take insulin can get too little sugar in their blood. This is a very bad illness that can even kill you if you don’t get help right away. Women who are pregnant can keep their blood sugar levels from dropping too low, which can be risky.

    Gestational diabetes can also lead to “a number of metabolic complications after delivery, such as low blood sugar for the baby, breathing problems, and neonatal jaundice.” There is a straight line between the mother’s blood sugar and the risk of these problems. This means that the higher the blood sugar, the higher the risk.

    FAQs Regarding Pregnancy with Type 2 Diabetes

    Does drinking plenty of water improve gestational diabetes?

    Hydration is good for everyone, especially gestational diabetics. Hydrating helps diabetic women avoid overeating, which is crucial to treating the illness.

    Women with gestational diabetes deliver early?

    Gestational diabetes may cause preterm birth. Most women with the disease have full-term pregnancies, however, problems may need early induction.

    Is nutrition responsible for gestational diabetes?

    Hormonal changes during pregnancy cause diabetes. When pregnant, eating more, exercising less, and having extra fat might cause insulin resistance.

  • (Polycystic Ovary Syndrome) PCOS and Fertility

    PCOS, which stands for polycystic ovarian syndrome, is a very common hormonal disorder in which the ovaries do not always produce an egg after the monthly cycle (which runs from the beginning of one menstrual cycle to the beginning of the next one). This causes infertility in women. It could make it more challenging to get pregnant. PCOS and fertility issues are believed to be quite widespread, affecting around one out of every five women.

    If you are diagnosed with polycystic ovary syndrome (PCO), you have a significantly increased number of follicles, which are fluid-filled sacs that are located on the ovaries and are responsible for the release of eggs during ovulation. However, just because you have polycystic ovaries does not always imply that you have PCOS. PCOS is a condition that is connected to having hormone levels that are not balanced, but having PCO signifies that your ovaries are somewhat different from what most women’s ovaries look like.

    Information for knowledge:

    • It is believed that between 8 and 13% of women of reproductive age suffer from polycystic ovarian syndrome (PCOS).
    • Around the globe, up to 70% of afflicted women do not get a diagnosis.
    • The most prevalent reason for not ovulating is polycystic ovary syndrome (PCOS), which is also one of the primary causes of infertility.
    • PCOS has been linked to a wide range of chronic health issues that may have an impact on both a person’s physical and mental well-being.
    • PCOS tends to run in families, however, there are ethnic differences in how the condition expresses itself and how it affects individuals.

    Symptoms of PCOS

    Polycystic ovary disease can have different signs in different people. The symptoms may change over time, and there isn’t always a clear reason why they happen.

    Some possible PCOS symptoms are:

    • Infertility, acne or sticky skin, too much hair on the face or body, male-pattern baldness or hair loss, and periods that are heavy, long, irregular, uncertain, or not present at all. Gaining weight, especially around the belly.
    • People who have PCOS are more likely to have other health problems, such as
    • Type 2 diabetes and high blood pressure
    • heart sickness and high cholesterol
    • Cancer of the lining of the uterus called uterine cancer was found.
    • PCOS can also lead to worry, sadness, and a bad view of one’s body.
    • People may look down on people who have certain signs, like infertility, fat, or hair growth that aren’t wanted.
    • This can have an impact on other parts of your life, like your family, relationships, work, and community work.

    Diagnosis Of Polycystic Ovarian Syndrome

    If at least two of the following are present, you may have polycystic ovary syndrome:

    After other possible reasons have been ruled out, signs or symptoms of high androgens include unwanted hair on the face or body, hair loss from the head, acne, or a high blood level of testosterone.

    Women with polycystic Ovary Syndrome have issues in that their cycles aren’t regular or don’t come at all after other reasons have been ruled out, and enlarged ovaries are seen on an ultrasound.

    Blood tests can show changes in hormone levels that are specific to a person, but these changes don’t happen to everyone. Polycystic ovary syndrome (PCOS) can cause women to have higher amounts of:

    In the ovaries, testosterone is an androgen hormone that affects hair growth; estrogen is an androgen hormone that encourages the growth of the endometrium, which lines the womb; luteinizing hormone (LH) is a pituitary hormone that affects hormone production by the ovaries and is important for normal ovulation; insulin is a hormone that helps the body use energy from food; and anti-Mullerian hormone checks the ovaries’ ability to become pregnant.

    Doctors also look at the fact that unpredictable cycles and ovulation can be a normal part of childhood or menopause. Having polycystic ovaries may run in the family, and women who have a history of PCOS or type 2 diabetes in their family are more likely to get it themselves. It’s also not always easy to see on an ultrasound, and many women with PCOS may have scans that don’t show they have polycystic ovaries.

    PCOS and Fertility
    PCOS and Fertility

    Treatment For PCOS

    Although polycystic ovary syndrome (PCOS) is an illness that cannot be cured, some treatment options may help lessen its symptoms.

    People who have irregular periods, problems getting pregnant, major acne, or quick hair growth should see a qualified medical professional.

    Some people with  (PCOS) polycystic ovarian syndrome, find that making adjustments to their way of life might help alleviate some of the symptoms of the condition. The maintenance of a healthy, well-balanced diet in conjunction with an adequate quantity of regular physical exercise may make it easier for an individual to reduce their risk of acquiring type 2 diabetes as well as their overall body weight.

    It’s possible that using birth control tablets, sometimes called the contraceptive pill or the pill, may help regulate menstrual periods and ease some of the symptoms that come along with them. Additional drugs may be used to treat acne as well as unwanted hair growth that is brought on by polycystic ovarian syndrome (PCOS).

    Complications And Problems From PCOS

    Women with PCOS often have high levels of androgen and have an increased risk for a variety of issues. These may vary from one individual to the next and include the following:

    Having difficulty affects fertility. Ovulation might be hampered when there are cysts present in the ovaries. That is the time of the month when one of your ovaries will release an egg. It is impossible to get pregnant if there isn’t an egg that’s in good enough shape to be fertilized by a sperm. Even if you have PCOS, there is a chance that you might still have a child. However, in order to achieve your goal, you may need to see a reproductive doctor and use treatment for infertility in women

    Problems with insulin and diabetes both. Your body may produce an excessive amount of androgens if it is resistant to insulin. If you have insulin resistance, the cells in your muscles, organs, and other tissues don’t absorb blood sugar very efficiently. This may lead to a variety of health complications. As a consequence of this, you run the risk of having an excessive amount of sugar circulating through your circulation. Diabetes is the name given to this condition, and it may lead to issues with both your cardiovascular and neurological systems. PCOS has also been linked to gestational diabetes, which is diabetes that develops during pregnancy.

    The syndrome of metabolism. The presence of this cluster of symptoms is associated with an increased risk of cardiovascular disease. High levels of triglycerides and low levels of HDL (“good”) cholesterol are among the symptoms, along with high blood pressure and excessive amounts of sugar in the blood.

    The following are some more frequent problems of PCOS:

    • Abortions or births that are too early
    • Depressive state
    • Concern or worry
    • Vaginal bleeding in addition to an increased likelihood of developing uterine cancer.
    • Problems falling asleep, including obstructive breathing.
    • Hepatitis, an inflammation of the liver

    Infertility in women with polycystic ovarian syndrome (PCOS) may be treatable in several ways. Some infertility treatments include making lifestyle adjustments, taking medication, or undergoing surgical procedures. In-vitro fertilization, more often referred to as IVF, is a choice; yet, it is not devoid of any potential negatives.

    PCOS and Pregnancy

    Female bodies make more androgens than usual when a woman has PCOS. It is common to think of these hormones as male hormones since men have much higher amounts of them than women.

    Androgens play a big role in how men’s sex parts and other male traits arise.

    Most of the time, androgens are changed into estrogen in women.

    Problems with ovulation

    High amounts of androgens make it hard for your eggs to grow and for them to come out at the right time. The name for this process is ovulation.

    Infertility in Women with PCOS, can’t get pregnant if a good egg isn’t released. Sperm can’t fertilize it. If you have PCOS, you might miss your period or have periods that come and go. This could be one of the first signs that something is wrong, like PCOS.

    How to control your period

    Birth control pills may be prescribed by your doctor. These pills contain estrogen and progestin that were made in a lab. By stopping the production of androgen, these pills can help you keep your period regular and treat PCOS

    If you can’t handle a pill that contains both estrogen and progestin, your doctor may suggest a pill that only contains estrogen.

    This pill is taken for about two weeks every month for one to two months. It’s also made to help keep your period in check.

    Pills that can help you ovulate

    If you are taking birth control pills for PCOS, you will not be able to get pregnant. But here are some medicines that might help you ovulate so you can get pregnant:

    • A drug called clomiphene (Clomid, Serophene) is used to block estrogen. It is taken at the start of your cycle.
    • If clomiphene doesn’t help you ovulate, you may be given metformin, a drug used to treat diabetes.
    • If clomiphene and metformin don’t help, your doctor may give you a drug that has both a follicle-stimulating hormone (FSH) and a luteinizing hormone (LH) in it. This medicine is shot into you.
    • If you’re taking Femara, letrozole is another drug that can help you ovulate. It’s sometimes taken when other drugs don’t work.

    How to Change Your Diet and Way of Life for PCOS and Fertility

    If you want to get pregnant, you should generally live a healthy life by eating better, working out regularly, not smoking, reducing your stress, and taking care of your diabetes and other health problems.

    Dealing with weight

    A lot of people with PCOS are overweight, but not all of them are. Hormones can change in some women when they gain a lot of weight. To get your hormones back to normal, you may need to lose weight if you are fat or overweight. If you lose 10 percent of your body weight, you might be able to better predict when your period will come. You should be able to get pregnant now.

    Your doctor may tell you to watch the size of your meals and eat a diet smaller in calories and fat. Some people find it hard to lose weight, though. You might be able to get help from a chef or doctor. It can also be helpful to write down your meals and snacks or use an app to keep track of your food.

    Taking care of blood sugar

    An awful lot of people who have PCOS also have insulin resistance. That’s when insulin doesn’t work right in your body. Insulin makes sure that your blood sugar stays the same.

    If you want to control your blood sugar, your doctor may tell you to eat foods that are lower in sugar and some types of carbs.  Fruits and veggies are good carbs. Some, like those in prepared foods, white bread, rice, potatoes, and sugar, you should stay away from, though. Another healthy food that can help with your blood sugar is fish, whole grains, chicken, and other lean meats.

    Working out

    Working out regularly can help you lose weight and build muscle. This may help lower insulin intolerance, which in turn may lower the amount of androgens in your body. In turn, that can help your PCOS.

    FAQs Related PCOS and Infertility:

    How does PCOS retain energy?

    Women with PCOS tiredness should avoid junk and fried food and eat B-complex vitamins, iron, and minerals. Yoga and regular exercise are effective PCOS-related chronic tiredness treatments, together with a balanced diet and decent sleep.

    Any PCOS-friendly foods?

    The PCOS diet includes low-glucose non-starchy fruits and vegetables, little low-fat dairy, omega-3-rich fish, lean red meat, poultry, lentils, and healthy grains.

    How can PCOS influence the mind?

    Anxiety, sadness, and eating problems may result from polycystic ovarian syndrome (PCOS), a hormone imbalance that causes infertility, obesity, and abundant facial hair in women.

  • What is Intracytoplasmic Sperm Injection (ICSI) Treatment?

    ICSI, or intracytoplasmic sperm injection, is a treatment for impotence. It is done in a lab by putting live sperm into someone’s eggs. An embryo (fertilization egg) can be made with this method. You can get a successful pregnancy through ICSI, which is a type of IVF. Medical professionals usually use ICSI when a person can’t have a child because of male infertility. When sperm is directly injected into an egg, it is called intracytoplasmic. The gel-like stuff in the middle of an egg is made up of water, salt, and other chemicals.

    How is ICSI not the Same as IVF?

    ICSI is one kind of IVF. When you get standard IVF, your doctor puts an egg on a lab dish next to thousands of sperm directly. It’s up to chance whether one of the sperm gets into the egg and fertilizes it. Conception, which is also called fertilization, doesn’t happen if none of the sperm touch the egg.

    Through the direct placement of a single sperm into a single egg, ICSI helps with the process of fertilization. Still, ICSI doesn’t promise that the egg will hatch.

    Your doctor will put the fertilized egg (embryo) into your uterus during both ICSI and standard IVF. If the egg sticks to the walls of your uterus, you are pregnant.

    What is ART, or Assisted Reproduction Technology?

    ICSI and IVF are both types of assisted reproductive technology (ART) that are used to treat infertility. ART refers to fertility techniques that are done in a lab and use eggs and sperm from outside of a person to start a baby.

    How well does Intracytoplasmic Sperm Transfer Work?

    ICSI is used in about six out of ten IVF processes. You have the same chances of getting pregnant with ICSI as you do with regular IVF. It is thought that between 50 and 80 percent of ICSI tries lead to fertilization.

    Why do we need the ICSI Procedure?

    ICSI works best for people who are having trouble getting pregnant with a boy. This procedure may be suggested by your doctor if someone has:

    • Anejaculation means not being able to ejaculate.
    • Their male sexual system is being blocked.
    • Not many sperm.
    • Not very good sperm.
    • When a man ejaculates, the sperm moves backward into his stomach.

    ICSI may also be needed if:

    • Embryos have not been made with traditional IVF.
    • The guy who is giving you the eggs is over 35 years old.
    • You’re trying to get pregnant with eggs or sperm that have already been frozen (cryopreservation).
    • Someone does an intracytoplasmic sperm injection.

    An OB/GYN who is also a fertility specialist might be able to help you. These doctors fix problems with the endocrine system that make it hard to get pregnant. They know a lot about finding and treating infertility and keeping a woman’s fertility

    What Takes Place Before Intracytoplasmic Sperm Injection (ICSI)

    The eggs and sperm must be collected by your doctor before ICSI can happen.

    To get an egg, these steps must be taken:

    • For ovulation induction, which is also known as ovarian stimulation, the person who is releasing the eggs gets doses of medicine for eight to fourteen days. This makes your ovaries make more than one egg at the same time so they can hatch. Next, a dose of Lupron, or human chorionic gonadotropin (HCG), will help the eggs finish maturing.
    • For egg extraction, your doctor will use transvaginal ultrasound to help guide a thin needle through the wall of your vagina and into your ovaries. A light anesthetic is used for this step, so it doesn’t hurt. Along with the needle is a sucking device that pulls out and catches the eggs.
    • On the same day that the eggs are taken out, sperm collection also happens, unless frozen sperm is used.
    • Sperm given by the person should not have intercourse or masturbation (no ejaculation) for two to three days before the sperm collection.
    • Masturbates at home or in a private room at a pregnancy center, and then ejaculates into a jar given by the lab. The lab must receive the samples no more than 60 minutes after the ejaculation.

    Right away, a semen study is done to check the quality, quantity, and movement of the sperm. Some people may need treatment to collect sperm if they have azoospermia, anejaculation, or backward ejaculation. This is also true for people who try to reverse an abortion but fail. In some cases, the hospital may be the better place for procedures like electroejaculation and tiny testicular sperm extraction. For later use in IVF at the clinic, the sperm may be frozen and stored in a lab. This is called “sperm banking.”

    During Intracytoplasmic Sperm Transfer, What Does it Happen?

    During ICSI, your doctor or nurse will:

      • Keep the fully grown egg in place on a lab dish with a pipette, which is a small glass tube with a suction tip.
      • uses a tiny needle to stop one sperm from moving and pick it up.
      • To get to the cytoplasm, the needle is put into the egg.
      • Puts the sperm into the cell’s cytoplasm.
      • Takes the needle off of the egg.

    What Comes Next After ICSI Treatment

    After ICSI, your doctor will check the fertilized egg in the lab for signs that it was fertilized successfully. A good egg that has been fertilized should split into cells and make a blastocyst in five to six days. Your doctor will look at the size and number of cells in the embryo to figure out when it’s most likely to become pregnant.

    On the fifth or sixth day after the egg removal process, the embryo transfer. Usually, the transfer is put off for a month or even a year. Your doctor will talk to you about when to have the egg transfer. Your doctor will use ultrasound to put a catheter (a long, thin tube) into your vagina and then inject the baby into your uterus. The baby has to connect to your uterus for you to become pregnant. Your doctor may tell you to wait at least two weeks before getting a pregnancy test.

    Benefits and Risks of ICSI Attempts

    Benefits:

    ICSI makes it possible for men who can’t have children or have low sperm count, bad morphology, or bad quality sperm to have children. Women over 35 who are having trouble getting pregnant have a better chance of getting pregnant with ICSI.

    Risks:

    The chances of multiple gestation, premature birth (even in singleton pregnancies), and congenital defects in the progeny are all greatly elevated by assisted reproduction. Most pregnancies conceived by in vitro fertilization end successfully, with the delivery of healthy babies.

    What are the Baby’s Risks if ICSI is Used?

    About 2% of babies born in the U.S. have genetic diseases, which means they had a health problem from the start. A further 1% of children born through ICSI are born with birth defects. Experts in medicine believe that these issues may be caused by the main reason for infertility, not by the fertility treatment itself. And this risk isn’t that big, since birth problems happen in only 2% of babies born each year.

    FAQs Regarding ICSI:

    How do people who use ICSI get better and what is their outlook?

    Recovery and prognosis depend on how the IVF process is done.

    When to See a doctor?

    You should get in touch with your doctor if you notice any of these symptoms:

    • When a fertilized egg implants outside of the uterus, this is called an ectopic pregnancy.
    • Getting sick.
    • Lost the baby.
    • Birth before time.

    Does ICSI make it more likely that you will have twins, triplets, or more?

    Your doctor may use ICSI to fertilize more than one egg to improve your chances of getting pregnant. You might have twins, triplets, or more if you decide to move more than one egg. A multiple pregnancy can make it more likely that the kids will be born early or have other problems.

  • What are Ovulation Days? Calculate Fertility Time with Ovulation Calculator

    What are Ovulation Days? Calculate Fertility Time with Ovulation Calculator

    Most people don’t know what is ovulation days. When an egg is fully grown, it leaves the ovary, moves down the fallopian tube, and is ready to be fertile. This is called ovulation. An egg will hatch inside one of your ovaries every month or so. The ovary lets go of the egg when it’s ready, and it goes into the fallopian tube on its way to the uterus and the waiting sperm. It has become thicker on the inside of the uterus to get ready for the fertilized egg.

    The uterus lining and blood will be shed if there is no conception. menstrual cycle happens when an unfertilized egg and the uterus wall fall out.

    Important Facts Regarding What is Ovulation Days

    • An egg has 12 to 24 hours to live after it leaves the ovary.
    • Most of the time, only one egg is released each time a woman ovulates.
    • Stress, sickness, or changes in the normal routine can all affect ovulation.
    • Light blood or spotting may happen to some women during ovulation.
    • It usually takes 6 to 12 days after ovulation for a fertilized egg to be implanted.

    Every woman is born with millions of eggs that are not fully developed yet. They are waiting for ovulation to start.

    • It is possible to have a menstrual cycle even if ovulation has not happened.
    • Even if you haven’t had your menstrual cycle yet, ovulation can still happen.
    • Middle pain” is the name for the pain some women feel near their ovaries when they ovulate.
    • If an egg doesn’t get fertilized, it breaks down and is taken up by the lining of the uterus.

    How to Keep Track of Your Time Of Ovulation

    A woman’s monthly cycle runs from the first day of her period to the first day of her next period. The standard length of a woman’s cycle is between 28 days and 32 days, but some women may have cycles that are much shorter or much longer. You can start figuring out ovulation on the first day of your last menstrual cycle (LMP) or 12 to 16 days before your next period is due. From the first day of the LMP, most women ovulate between Day 11 and Day 21 of their cycle.

    Many people call this part of a woman’s cycle the “fertile time or fertile window” because having sex during this time makes it more likely that she will get pregnant. Ovulation can happen at different times during a cycle, and it might happen on a different day every month. It is important to keep track of your cycle, and luckily, there are a lot of free fertility charting tools that can help women find their most fertile days.

    The Two Parts of the Ovulation Cycle

    The follicular phase is the name for the first part of the cycle. This phase starts on the first day of the last menstrual period (LMP) and lasts until the egg is released.

    This first part of the cycle length can last anywhere from 7 to 35 days – to 40 days, depending on the woman.

    This part of the cycle lasts from the day of ovulation until the next period starts. It is called the luteal phase. There is a more accurate timetable for the luteal phase, which usually starts 12 to 16 days after ovulation.

    This means that the day you ovulate will tell you how long your cycle is. This also means that things outside of your control, like worry, illness, or changes to your normal routine, can throw off your cycle and cause your period to come at a different time. That old idea that worry can make your period worse is only half true. Your ovulation can be affected by stress, which affects when your period will come. However, if you’re stressed around the time of your period, it won’t come later because the date was already set 12 to 16 days earlier!

    One way to keep track of when ovulation happens is to use a basal temperature and pay attention to changes in the cervical mucus. The fluid in the cervix will change into something wet and slippery that looks like “egg whites” right before and during ovulation. A basal thermometer helps you keep track of a rise in body temperature, which means that ovulation has just happened.

    Egg and pregnancy testers are two more ways to keep track of your cycle. By keeping track, a woman can get a better idea of when she can get pregnant and when she can’t during her monthly cycle. There is nothing you can do to improve your chances of getting pregnant after ovulation. The next thing you should do is start looking for signs of an early pregnancy. You can look at and print out an ovulation calendar to help you understand your pattern better.

    From Your Period to Ovulation (the details you might not know!)

    When your period starts, your estrogen levels are low. It is your hypothalamus’s job to keep your hormone levels in check. It sends a message to your pituitary gland, which delivers the follicle-stimulating hormone (FSH). Some of your follicles will turn into developed eggs when this FSH is released. One of these will grow into the main follicle and release a developed egg. The other follicles will break apart.

    The follicles release one more hormone, estrogen, as they grow up. Because there is a lot of estrogen, the brain and pituitary gland will know that there is a developed egg. Then, a luteinizing hormone (LH) is produced. This is called an LH spike. In 24 to 36 hours, the LH increase makes the egg break through the ovary wall and start its trip down the fallopian tube to be fertilized. Ovulation Predictor Kits (OPKs) find this LH spike and use it to work. The corpus luteum is the name of the cell from which the egg was released. It will release progesterone, which helps the lining of the uterus get thicker and ready for implantation. During the luteal part of your cycle, which lasts for 12 to 16 days, the corpus luteum makes progesterone.

    The corpus luteum continues to make progesterone for a growing pregnancy until the placenta takes over if sperm fertilizes the egg. You can start looking for signs of pregnancy up to a week after sperm fertilizes the egg. You can also use an Early Detection Pregnancy Test up to 7–10 days after your ovulation date to check for pregnancy.

    If sperm does not fertilize the egg, the egg breaks down after 24 hours. Your hormone levels will drop at this point, and about 12 to 16 days after ovulation, the lining of your uterus will start to shed. This is your period of bleeding, and we’re back to day 1 of your cycle. After that, the trip starts all over again.

    Knowing when a woman ovulates is one of the most important things she should know about her body because it affects her ability to get pregnant or not get pregnant.

    FAQs Regarding Signs of Ovulation

    Your ovulation period is how long?

    Ovulation symptoms may continue five days before, one day after, and two days following for many women. The absence of indications of ovulation doesn’t indicate you’re not ovulating.

    Your ovulation period is how long?

    Ovulation symptoms may continue five days before, one day after, and two days following for many women. The absence of indications of ovulation doesn’t indicate you’re not ovulating.

    Is Ovulate without a period possible?

    How irregular periods affect ovulation and fertility. Despite their association, ovulation may occur without menstruation. Women with irregular periods commonly experience this. Alternatively, monthly bleeding without ovulation is conceivable.

     

  • Main Reasons of IVF Failure

    Main Reasons of IVF Failure

    “Why does IVF fail?” may be on your mind. We have heard a lot of good things about in-vitro fertilization (IVF) methods from family, friends, and the internet. However, we don’t hear much about IVF implantation failure because it’s usually a very touchy subject for people who want to have children. This blog post breaks the taboo and talks about reason of IVF Failure.

    The most recent success rates we sent to the Human Fertilization and Embryology Authority (HFEA) show that the treatment of IVF success rate is 40.6% for getting pregnant and a live birth rate of 32.5%. Sometimes, IVF doesn’t work for people, and they don’t get pregnant or have a live birth. There are several reasons for this.

    What Are The Main Reasons Of IVF Failure:

    There are several things that can go wrong with IVF. One of these reasons is recurrent implantation failure, which happens after a few days. This happens when the growing baby doesn’t stick to the wall of the uterus, stopping a link from being made. There are also problems with growing in the baby and a lot of DNA variation. No matter what the reason for IVF failure but, it can be painful and mentally tiring. Here are some main reasons why IVF fails:

    1. Sperm Abnormality

    Sperm that isn’t working right is a reason of IVF failure. A doctor will carefully look at the sperm for any problems during the treatment. If the sperm isn’t shaped right, the egg probably won’t get fertilized. During this process, the sperm will have to break through the egg’s outer layer and release half of its genetic material. This will allow a healthy baby to grow. Your ability to choose good sexes during the process is important if you want to have a healthy pregnancy. If not, a doctor might have to do genetic testing before the pregnancy to find these problems.

    2. Female Age

    As women age, the quality and number of their eggs decline. It’s a well-known fact that women have a lower chance of getting pregnant as they age. However, a drop in egg number and quality also lowers the chances of a clinical pregnancy or a live birth after IVF treatment.

    “According to our success rates, women up to the age of 35 have the highest chance of IVF success: 47% for clinical pregnancy and 38% for live birth,” says Dr. Ritu Agrawal, co-founder of The RITU IVF Center and one of the most well-known fertility experts in India

     3. Quality of The Embryo

    In the IVF clinic for fertility treatment, the eggs from the female and the sperm from the donor (male) are put together to try to make a baby. Embryo implantation may look healthy in the lab, but there is a chance that they won’t settle into the uterus because of a problem that can’t be seen. Scores are used by our fertility specialist to rate the eggs’ quality and pick the best ones to put back into the uterus. We also use time-lapse images (embryoscope) to keep the embryos warm until they reach the blastocyst stage, which is when embryos are 5 days old. There is a camera inside the closed box that takes pictures of the embryo quality in every 10 to 20 minutes. This is called the embryoscope. The screen on the outside of the embryoscope lets us see how the embryos are growing. This way, we don’t have to take the embryos out every day to check on them, which keeps them in a safe setting. We can also play back the video recording and see how the embryos changed overnight. This lets us pick the best embryo transfer in order to get pregnant.

    4. What the Ovarian Does

    At the start of IVF treatment, the woman has to give herself a shot of follicle-stimulating hormone (FSH), a fertility hormone, every day. The goal of this injection is to make more eggs. Some women’s ovaries don’t react properly to this medicine, so they don’t make enough eggs to collect. Low ovarian reserve means that older women already don’t have many eggs, so this is especially true for them.

    “If the ovaries don’t respond well, it doesn’t mean the end of the IVF treatment,” says Dr. Ritu. The case might be able to get better with more research and changes to the medicine. AMH levels in the blood and the number of antral follicles seen on an ultrasound scan are used to figure out the ovarian reserve. The amount of ovarian reserve would tell you the best way to activate your ovaries and get them to make a good number of eggs.

    5. Problems with Implants

    This means that the eggs did not grow inside the uterus. There could be uterine cysts, an early rise in progesterone levels, an endometrial covering that is too thin, or an infection in the uterus leading to infertility. “If an embryo doesn’t implant, it’s not your fault,” says Dr. Ritu. “Most of the time, problems with implantation are out of anyone’s control.” We put together a wide range of tests to look for the reasons why implantation might not have worked.

     6.  Way of lifestyle

    As with a normal pregnancy, living a healthy life before and during IVF is likely to make it easier to get pregnant. Giving up smoking a few months before you start IVF is a good idea because it has been shown to hurt fertility. In addition to eating well and working out daily, reaching a healthy weight will also help you.

    7. Chromosomal Abnormalities

    Sometimes IVF fails because the eggs don’t have the right chromosomes. This means that there is a piece of chromosomal DNA missing, extra, or not arranged right in the baby. The body then rejects the baby, which means the IVF doesn’t work. Chromosomal abnormalities can be passed down from one parent to the child or form during the early stages of cell division.

    As per Dr. Ritu Agarwal, the best IVF doctor in Jaipur, “Chromosome problems are most likely to be present in embryos from women over the age of 35.” But don’t let that stop you. We can check all 23 pairs of chromosomes in the embryos to see if they have any inherited genetic or gene problems, and only the healthy embryos will be replaced.

    Reproductive immunology is the idea that an egg or fetus is rejected because the body’s immune cells are working too hard. There is a chance that your immune cells are fighting the baby if you have tried IVF but have not been able to get pregnant. Reproductive immunology might be able to help you figure out why your IVF cycles keep failing and, if your immune system is responding in this way, give you a way to treat it.

    Conclusion:

    Failure of IVF is distressing. Mental and emotional health and money might suffer. Support will help you manage these feelings. Counseling and infertility treatment are alternatives.

    Breaks from therapy might also assist. This may alleviate stress and prepare you for another treatment cycle. Many physicians advise waiting four to six weeks before undergoing IVF again, following a negative pregnancy test.

    Identifying the Reason of IVF Failure might enhance future efforts. Your doctor may recommend genetic testing if you have a hereditary condition.

    Different drugs affect your body differently. Inducing ovulation using ovarian stimulation medications may cause reproductive system inflammation. Your doctor will adjust your stimulation regimen based on your reaction.

    Many couples struggle after their first unsuccessful IVF process. But there are various methods to become parents.

    FAQs Regarding IVF Fail Reasons:

    What causes most IVF failure?

    Despite its complexity, embryos that fail to implant on the uterine lining are a common cause of IVF failure. It may have been delivered to the uterus with an unsuitable lining or not attached properly.

    After 3 unsuccessful IVF rounds, what next?

    After your third unsuccessful IVF cycle, consider a second opinion, more diagnostic testing, reevaluating your treatment plan, or other reproductive therapies.

     

  • Fallopian Tube Blockage – Signs, Symptoms, and Treatment

    Fallopian tubes link the ovaries to the uterus and are reproductive systems for women. Periods usually happen in the middle of each month. During ovulation, an egg is carried from an ovary to the uterus by the fallopian tubes.

    The fallopian tube is also where conception takes place. If sperm joins with an egg, the egg goes through the tube to the uterus where it will be implanted.

    It is impossible for sperm to reach the eggs and for the fertilized egg to return to the uterus if a fallopian tube is blocked. Scar tissue, infections, and pelvic adhesions are common things that can block the fallopian tubes and cause of infertility.

    Symptom That Your Fallopian Tube is a Block

    Most of the time, a blocked fallopian tube may not make you feel sick. A lot of women don’t know they have blocked tubes until they are having trouble getting pregnant.

    When the fallopian tubes get blocked, there may be mild, constant pain on one side of the belly. This often happens with a hydrosalpinx, which is a type of blockage. This is when fluid fills up a blocked fallopian tube and makes it bigger.

    Some of the things that can cause a blocked fallopian tube have their signs and symptoms. As an example, endometriosis can lead to painful, heavy periods and pain in the pelvis. It may be recommended to have your fallopian tubes blocked.

    How it Affects Fertility

    Infertility is often caused by ovarian tubes that are blocked. The fallopian tube is where the sperm and egg sexually transmitted to become one. If the tubes get clogged, they might not be able to connect.

    If both tubes are completely blocked, it will not be possible to get pregnant without surgery. You might be able to get pregnant even if your fallopian tubes are partly blocked. But the chance of having an ectopic pregnancy goes up.

    The reason for this is that a blocked egg finds it harder to get to the uterus after being fertilized. If these things happen, your doctor may suggest in vitro fertilization (IVF), but only if the treatment is possible.

    Causes Of Fallopian Tube Blockage

    Most of the time, scar tissue or adhesions in the pelvis block the fallopian tubes. These can be caused by several things, such as

    • Inflammatory disease of the pelvis: This illness can leave scars or hydrosalpinx.
    • Having endometriosis: Endometrial tissue can build up in the woman’s fallopian tubes and block them. Endometrial tissue that is on the outside of other organs can also stick together and stop the fallopian tubes.
    • Some STIs, or sexually transmitted diseases: Going through chlamydia or gonorrhea can leave scars and lead to pelvic inflammatory disease.
    • Ectopic pregnancy in the past: The fallopian tubes may get scars from this.
    • Lumpy skin: These growths, especially where they connect to the uterus, can block the end of the fallopian tube.
    • After having stomach surgery: If you had abdominal surgery in the past, especially on the fallopian tubes, pelvic adhesions can form and stop the tubes.
  • What is Ovarian Stimulation in IVF?

    What is Ovarian Stimulation in IVF?

    There are a lot of things about in vitro fertilization (IVF) that help it work, or lead to a good baby. One of these parts is the process of ovarian stimulation, which tries to make ovulation happen before other methods are used. The goal of stimulating the ovaries is to make it more likely that a woman will get pregnant.

    Let’s talk more about how ovarian stimulation works to help you and your partner know what to expect during your IVF treatment.

    What is the Goal of Ovarian Stimulation?

    The goal of ovarian stimulation is to make it work like the body’s normal ovulatory cycle, in which chemicals make the eggs develop and release them.

    IVF stimulation is done with pills or hormone shots or injection to help more than one egg develop at the same time, which increases the chance of getting pregnant. When hormones are used to stimulate the ovaries, they also help improve the quality of the eggs.

    Ovarian stimulation is often used to get eggs during the second part of IVF treatment. You can use these eggs right away or save them for another time. This method is mostly used for people who have been told they have a problem with ovulation because it helps them ovulate.

    Stages of IVF Stimulation of the Ovaries:

    There are two main kinds of ovary stimulation:

    1. Long Protocol
    2. Blocker Protocol

    Long Protocol

    The usual way to do things is to follow a long routine. It starts about a week before the next period is supposed to start. GnRH-analogue, or gonadotropin-releasing hormone, is given to stop the ovary from doing anything on its own. This is done to stop the eggs from getting out so that a medical team can get them. Once the menstrual cycle starts, the patient gets hormone shots every day and is watched for two weeks. At the end of that time, the eggs are taken.

    Blocker Protocol

    Once the monthly cycle starts, the antagonist procedure begins. At this point, hormone shots are given to speed up egg maturation so that more eggs can be collected during the extraction stage. When the long plan doesn’t work, this is often the next step. It is also done when a woman has polycystic ovaries or a small number of eggs left in her ovaries.

    Ovarian Stimulation Process

    During ovarian stimulation, chemicals called follicle-stimulating hormones (FSH) and luteinizing hormones (LH) are used to help make more eggs, make them mature, and release them. To start the process, these hormones are given over the course of two weeks.

    Depending on how long it takes the eggs to grow, this stage can last longer for some women. One study in the Journal of In Vitro Fertilisation and Embryo Transfer found that women who didn’t respond well to a certain dose of FSH did respond well to a higher dose of the hormone the next time around.

    The goal of using FSH is to raise estrogen levels and help ovaries grow since some of them die when the body’s FSH levels go down. It is important that these amounts stay high so that more eggs can be made. To raise LH, the amount of estrogen needs to be high since this hormone helps start menstruation. In order for IVF to work, the eggs have to be taken out before the woman ovulates.

    What to Look For

    As you might expect, time is very important when it comes to stimulating the ovaries with hormones. Every step of the process needs to be done carefully and at the right time. The process can have to start over if there is even a small problem or delay.

    The physical parts of the whole process can also be stressful, but they can also give people hope. During the process of stimulating the ovaries, there are a few things to keep in mind. Here are a few things to remember.

    Taking Care of Your Medicines

    The hormone shots are just one of the ways that the IVF procedure is treated with medicine. Most people have to give themselves the shots and take pills and patches that are given to them. Again, just like with IVF shots, it’s important to time all of your medicines right so that your body can respond to the treatment.

    Along with taking normal medicine, it’s important to keep track of hormone levels with blood tests. With these tests, the practitioner can figure out when and how to make changes. Appointments to look at an ultrasound are also a part of the treatment.

    Tests and Touring

    Some people may have to drive a lot for regular tests and meetings, especially if the treatment place is in a different city or town. During the IVF process, it should be easy to stay in touch with the medical team by phone and email, but you’ll need to be there for any physical tests.

    Stress and Changes in Mood

    During the process of stimulating the ovaries, the hormones and medicines that are needed can make a person feel bad. Even though it may seem like the treatment to stimulate the ovaries is causing these mood changes, research has shown that this is not the case.

    Problems and Harmful Effects

    In addition to stress, fear, and worry, the medicine and hormone shots used in ovarian stimulation can have physical side effects. A rash or swelling at the treatment site can be a sign of mild illnesses. People have also said that their breasts hurt, they feel full, and they have stomach pain.

    Some patients have had more than one kid, usually twins or more because the treatment can cause more than one egg to mature at the same time. This means that more than one egg can be fertilized. There can also be problems like babies being born early or even losses.

    Services from Ritu IVF

    Ritu IVF Center is the best place in the Jaipur area for fertility care, treatment, and therapy. Some of the best infertility care experts in India work at our state-of-the-art center. The RITU IVF Fertility team uses a medical method that is backed by proof and combines it with caring treatment and individual care at every step. Our treatment plans can be changed to fit your needs. Contact us today to talk about your fertility questions and let us help you find hope on your IVF path.

  • IUI Treatment Procedure – Intrauterine Insemination Infertility Treatment

    IUI Treatment Procedure – Intrauterine Insemination Infertility Treatment

    The medical treatment known as intrauterine insemination (IUI) is used to treat infertility. IUI increases the likelihood of becoming pregnant by implanting specially prepared sperm directly into the uterus, the organ in which fetal development occurs. The process is also referred to as artificial insemination in certain circles.

    During an IUI procedure, sperm are introduced into the uterus while an ovary releases one or more eggs. The fallopian tube, which links the uterus to the ovaries, is where it is hoped that the egg and the sperm count will eventually fuse together to form a baby. If this does occur, it will result in the chance of pregnancy.

    The timing of an intrauterine pregnancy may be coordinated with a woman’s menstrual cycle. One of the two ovaries will release an egg at some point throughout the monthly cycle. Or, in conjunction with intrauterine insemination (IUI), fertility medicines may be injected to stimulate egg production in the ovaries. The specific procedure used is determined by the underlying causes of infertility.

    Why was the IUI Procedure Executed?

    Whether or not a couple or a person can conceive rests on many things. Most of the time, intrauterine insemination is used on women who have:

    Donor Sperm: This is sperm that was given to you by someone you may or may not know. It’s a choice if you’re single, your partner doesn’t have sperm, or the sperm isn’t good enough for you to get pregnant. Intrauterine insemination is the method most often used to get pregnant for people who need to use donation sperm. Donor sperm comes from labs that have been approved, and it is thawed before the IUI process.

    Unexplained Infertility: IUI is often the first treatment for people who can’t get pregnant for no clear reason. Usually, it is taken with medicines that help the ovaries make eggs.

    Infertility related to endometriosis: When tissue that looks like the lining of the uterus grows outside of the uterus, it can make it hard to get pregnant. Endometriosis is the name for this. When this is the reason for infertility, the first step in treatment is often to use medicine to get a good-quality egg and do IUI.

    Mild Male Factor Infertility: This is also called subfertility. Semen, the fluid that has sperm in it, can make it hard for some couples to get pregnant. A test called “semen analysis” looks at the number, size, shape, and movement of sperm to see if there are any problems. These problems are checked for by analyzing sperm. Some of these problems can be solved by IUI. This is because getting the sperm ready for the process helps separate the good ones from the bad ones.

    Cervical Factor Infertility: Problems with the cervix can make it impossible to have a baby. The cervix is the thin part of the uterus at the bottom. It gives the vagina and the uterus a way to connect. During ovulation, the cervix makes mucus when the ovary releases an egg. The mucus helps the sperm move from the uterus to the fallopian tubes, where the egg is waiting. But if the mucus in the cervix is too thick, it could get in the way of the sperm. Sperm can also be stopped from getting to the egg by the cervix. The cervix can get thicker if it gets scarred, which can happen after a biopsy or other treatments. IUI skips the cervix to make it more likely that you will get pregnant. It puts the sperm right into the uterus and makes more of them ready to meet the egg.

    Ovulatory Factor Infertility: IUI can also help people who can’t have children because they can’t get their eggs to mature. Some of these problems are not ovulating or not making enough eggs.

    Semen Allergy: Proteins in sperm rarely cause a reaction in people who are allergic to them. When the penis sends sperm into the vagina, the area where the sperm hits the skin starts to burn and swell. A condom can keep you from getting sick, and it can also keep you from getting pregnant. IUI can make it possible to get pregnant and stop the allergy symptoms from being painful. Before the sperm is put in, many of the proteins in the sperm are taken out.

    Your Level of Preparation

    Before beginning the real treatment, there are a few essential tasks that must be completed, including the following:

    Keep an eye out for Ovulation: Because the timing of IUI is so important, it is essential to look for indicators that the body is getting ready to ovulate. You might do this by making use of a urine ovulation predictor kit that is designed for at-home usage. It is able to identify when an increase or release of luteinizing hormone (LH) occurs in your body. LH is the hormone that induces the ovary to release an egg. You might also have a procedure known as transvaginal ultrasonography, which captures pictures of your ovaries and the development of your eggs. An injection of human chorionic gonadotropin (HCG) or other medications may also be administered to you in order to induce ovulation at the optimal period. This may result in the release of one or more eggs.

    Performing the surgery at the optimal time: IUI procedures are often performed one or two days after ovulation has been confirmed via diagnostic testing. Your physician will most likely have a strategy outlined for the time of your treatment as well as what to anticipate prior to the appointment.

    Getting the sample of sperm ready: At the recommendation of your physician, your spouse brings in a sample of his sperm. Alternatively, one may thaw and prepare a vial containing frozen donor sperm. The sample is cleaned in such a manner that it separates the sperm that are highly active and healthy from the sperm that are of poorer quality. In addition, washing eliminates components that, if introduced into the uterus, might result in adverse responses such as severe cramping. If a small but highly concentrated quantity of healthy sperm is used, there is a greater chance of the couple getting pregnant.

    During the procedure

    You insert your legs into the stirrups while lying down on the exam table. The vaginal walls are opened using a speculum, a hinged instrument made of plastic or metal. Medical staff do the following throughout the procedure:

    • Places a vial of viable sperm at the end of a catheter, which is a long, thin, flexible tube.
    • Intravaginal catheter insertion; cervix pierced; uterus reached.
    • Introduces the sperm sample into the uterus by forcing it via the tube.
    • The catheter is withdrawn, then the speculum is taken out.
    After the procedure.

    You’ll lay on your back for a short while after the sperm has been implanted in your uterus. After the operation is over, you may go home and change into your regular clothes. After the operation, you may have some mild spotting for up to two days.

    Results for Intrauterine Insemination (IUI) Treatment

    Do not take a home pregnancy test for two weeks. The results of premature testing might be:

    False-negative. Even if you could be pregnant, the test turns out negative. If pregnancy hormones are not yet detectable, you may obtain a false-negative test.

    False-positive. The test will show a positive result for pregnancy even if you are not pregnant. Taking fertility drugs like HCG that are still in your system might cause a false-positive result.

    About two weeks following the results of your at-home pregnancy test, you may be scheduled for a follow-up appointment. A blood test, which is more sensitive to the presence of pregnancy hormones after an egg has been fertilized by sperm, may be performed during the visit.

    You may attempt IUI again before moving on to other fertility treatments if you don’t get pregnant the first time. In order to increase the likelihood of conception, the same medication is often administered for three to six cycles.

    Conclusion:

    Infertile couples might find hope and potential through IUI. Working with healthcare specialists to discover the best strategy for unique situations requires patience and persistence.